PRODUCTS
Alkali-resistant protein A medium Mab SE
classification:Affinity chromatography
classification:Antibody purification packing
MabSE A is an agarose bead with an average particle size of 75 um coupled with protein A protein ligand that has undergone an alkali-resistant mutation.
Product Overview
Mab Crystarose SE A is a protein A ligand that has been conjugated to highly cross-linked agarose beads through an alkaline-resistant mutation. The resulting agarose resin remains stable for extended periods in 0.1–0.5 M NaOH solutions, enabling its use in more demanding production environments. This significantly extends the resin’s service life and reduces production costs. Alkali-resistant protein A agarose resin has a wide range of applications and can be used to purify most polyclonal and monoclonal antibodies. Its features include high sample throughput, fast flow rates, and high chemical stability, enabling it to withstand online washing with up to 0.5M NaOH solution.
Product Components
|
Components |
C612001 |
C612002 |
C612003 |
|
Mab Crystarose SE A |
5ml |
25ml |
150ml |
Storage conditions
The product can be stored long-term in 20% ethanol at 4°C-8°C.
Technical specifications
|
Technical specifications |
|
|
Matrix |
4% highly cross-linked agarose gel |
|
Average particle size |
75µm |
|
Ligand density |
≈6 mg recombinant protein A/ml |
|
Dynamic loading capacity |
≈30 mg human IgG/ml |
|
Buffer solution |
All standard buffer solutions |
|
Coupling method |
Epoxy activation |
|
pH Stability (Long-Term) |
Operating pH 3–12; pH range up to 2–12 during in-situ cleaning |
|
Maximum Flow Rate |
800 cm/h |
|
Storage Solution |
20% ethanol |
|
Storage Temperature |
4–8°C |
Key words:
Alkali-resistant protein A medium Mab SE